ERYTHROCYTE METABOLISM

Erythrocyte Metabolism

Previous studies from this laboratory on the preservation of erythrocytes stored in vitro have shown that the storage lesion, as characterized by the decline in level of organic phosphate esters, may be reversed by incubating the aged cells with certain purine nucleosides (1). Pyrimidine nucleosides were ineffective in this respect, as was the addition of the purine bases and ribose, alone or i...

Erythrocyte Energy Metabolism in Hereditary

The incorporation of extracellular orthophosphate-32P into cellular ATP, 2,3-diphosphoglyceric acid, and inorganic phosphate has been measured over a period of 6 hours in vitro in red blood cells from normal subjects and from patients with hereditary spherocytosis who had undergone splenectomy. The pattern of labeling of the intracellular compounds was found to be the same in both types of red ...

Pyridine nucleotides in erythrocyte metabolism.

Pyridine Nucleotides in Erythrocyte Metabolism * RUTH

In recent years investigations of erythrocyte metabolism have been concerned with the interrelationships of enzymes, coenzymes, substrates, cofactors, and pH, inter alia (1-8). Although data have accumulated on these various aspects of the metabolism of normal and pathological erythrocytes, little direct information has been available heretofore on pyridine nucleotide coenzymes, despite their i...

Studies on copper metabolism. XXXI. Erythrocyte copper.